Nixon is a city, self-described as a "compact neighborhood," at U.S. Highway 87 and the junction of Karnes, Gonzales and Wilson counties; alongside the Clear Fork Creek in the Juan J. Tejada League, in the U.S. state of Texas. Approaching 100 city blocks, the Nixon urban-area is defined by its schools at its north-end in the neighborhood of Rancho; with the southwest boundary hosting its industrial park and meat packing facilities, upon the 87-corridor towards Pandora and the county seat of Floresville.